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New index may predict death risk after abdominal surgery infection

NCT ID NCT06901544

Knowledge-focused Sponsor: Ain Shams University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether the Capillary Leak Index (CLI), a score based on routine blood tests, can predict which patients are at higher risk of dying after developing a serious abdominal infection following surgery. Researchers followed 100 critically ill adults in the ICU for 28 days. The goal was to see if a higher CLI on admission was linked to a greater chance of death, which could help doctors identify the sickest patients sooner.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could give doctors a simple tool to identify high-risk patients earlier after abdominal surgery, potentially improving care.
What could go wrong
This is a small, completed observational study, not a treatment trial. The index may not prove reliable enough for routine use in other hospitals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

100 people

The number who actually took part.

Started

Mar 2025

Finished

Aug 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

ICU Patient Post operative abdominal sepesis

Ages

18 years and older

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age: ≥18 years old presented with Post-operative intra-abdominal sepsis due to secondary peritonitis. * Sex: Both sexes. * Post-Operative secondary peritonitis eg. Perforated viscus and abdominal abscess. * Estimated length of ICU stays ≥48 hrs. Exclusion Criteria: * Patient refusal. * Advanced Liver diseases According New MELD score ≥ 20 )Kamath et al.,2001) * Renal diseases (Moderate decrease in GFR 30-59 ml/min/1.73m²--Severe decrease in GFR 15-29 ml/min/1.73m²--Kidney failure less than 15 ml/min/1.73m² or on Hemodialysis). * Pregnancy. * Primary peritonitis. * Tertiary peritonitis. * Mortality within first 48hrs of ICU admission. * Advanced malignancy ( Stage III localized malignancy with spreading lymph nodes Stage IV spreading to Other parts of the body such as to the liver, lungs and bones).

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Conditions

The condition(s) this trial relates to.

appendicitis intestinal obstruction Intraabdominal Infections Sepsis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Appendicitis acute Intestinal obstruction Intra abdominal infections Perforated viscus

Contacts and locations

Locations

  • Surgical intensive Care Unit, Ain Shams University Hospitals.

    Cairo, Cairo Governorate, 7154411, Egypt

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