Teen cannabis study seeks clues to relapse in brain chemistry
NCT ID NCT05396638
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how cannabis use changes natural brain chemicals in adolescents aged 14 to 25. Researchers will measure cannabinoid and endorphin levels in blood to find markers that could tell which teens might relapse and which stay sober. The goal is to better understand cannabis's effects on the brain, not to test a treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Started
-
Oct 2022
- Expected to finish
-
Dec 2026
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
14 to 25 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. 14 to 25 years of age. 2. Use cannabis at least twice a week for the past month. Exclusion Criteria: 1. Refusal of valid written consent, 2. Current psychosis, 3. Obvious intoxication, 4. Current risk of suicide, 5. Violence sufficiently great to interfere with evaluation or to endanger evaluators, 6. Obvious intellectual deficiency as noted during the informed consent process, or inability of patient or family to comply with the study protocol. 7. Use of other illicit drugs in the past 90 days by self-report or detected by urine drug test. 8. Use of opioid medications for medical or recreational purposes currently or within the past 90 days. 9. Does not have access to an Internet connected devise or cannot use Zoom.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Cannabis use are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University of Colorado Anschutz Medical Campus
Aurora, Colorado, 80045, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a website help people cut back on cannabis?
- Brain scans probe why cannabis hits men and women differently
- Can rewards and remote coaching help people cut back on cannabis?
- Can a phone app curb cannabis use in early psychosis?
- Can a sleep pill curb cannabis addiction?
- Pharmacies vs. street: does regulated cannabis improve health?