Can cannabis cause falls in older women? new study investigates
NCT ID NCT03633721
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how smoking cannabis affects balance, walking, and attention in 25 older women, some with HIV and some without. Participants smoked either a low-THC cannabis cigarette or a placebo, then did walking and thinking tests. The goal was to understand why cannabis users in earlier studies had more falls.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- cannabis (THC cigarettes)
- What this could lead to
- If successful, this could help explain why some older women who use cannabis have more falls, and guide safer use recommendations.
- What could go wrong
- This is a small, early-phase study with only 25 participants, so results may not apply to everyone. It looks at short-term effects, not long-term safety.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
-
25 people
The number who actually took part.
- Started
-
Oct 2020
- Finished
-
May 2022
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
40 to 70 years
- Sex
-
Female participants only
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. current cannabis use (within 6 months) based on self-report 2. able to perform study procedures, including ability to ambulate independently 3. adequate hearing and vision 4. for HIV+ women use of stable HAART for at least 6 months. Exclusion Criteria: 1. pregnancy 2. current illicit drug use other than cannabis 3. request for substance use treatment 4. current parole or probation 5. recent history of significant violent behavior (within 12 months) 6. major current Axis I psychopathology (e.g.,bipolar disorder, suicide risk, schizophrenia) 7. current use of psychiatric medication known to influence cognition 8. significant uncontrolled medical illness (such as uncontrolled diabetes or hypertension, clinically significant laboratory abnormalities, liver function tests (LFTs)\>3x upper limit of normal) 9. history of active heart disease within 12 months 10. history of dementia 11. severe hand tremor 12. history of Central Nervous System (CNS) diseases or injury 13. poor English fluency. All participants will be consented and compensated for their effort as approved by the Institutional Review Boards (IRBs) of each participating institution (see human subjects).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Montefiore Medical Center
The Bronx, New York, 10461, United States
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