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New drug cocktail shows promise for three tough cancers

NCT ID NCT05077709

First seen Apr 14, 2026 · Last updated May 25, 2026 · Updated 9 times

Summary

This study tested a combination of two drugs (IO102-IO103 and pembrolizumab) as the first treatment for people with advanced lung, head & neck, or bladder cancer that has spread. The goal was to see if the combo could shrink tumors and delay cancer growth. A total of 63 patients took part in this early-stage trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope

    Duarte, California, 91010, United States

  • Guys and St Thomas Hospital

    London, United Kingdom

  • Hospital Clínico Lozano Blesa

    Zaragoza, Zaragoza, 50009, Spain

  • Hospital Clínico Universitario de Valencia

    Valencia, Valencia, Spain

  • Hospital Universitari de Girona Doctor Josep Trueta

    Girona, 17007, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, 28041, Spain

  • Hospital Universitario Fundación Jiménez Díaz

    Madrid, 28040, Spain

  • Hospital Universitario Ramon y Cajal

    Madrid, 28034, Spain

  • Hospital Universitario Virgen Macarena

    Seville, Sevilla, 41009, Spain

  • Hospital Universitario Virgen de la Victoria

    Málaga, 29010, Spain

  • Hospital Vall d'Hebron

    Barcelona, 08035, Spain

  • Institut Català d'Oncologia (ICO) Badalona (Catalan Institute of Oncology)

    Barcelona, 08916, Spain

  • Mid Florida Hematology and Oncology Center

    Orange City, Florida, 32763, United States

  • Montefiore Medical Center

    The Bronx, New York, 10467, United States

  • Oregon Health & Science University

    Portland, Oregon, 97239, United States

  • UC Davis Cancer Center

    Sacramento, California, 95817, United States

  • University of California San Diego

    San Diego, California, 92093, United States

  • University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • University of Toledo Medical Center

    Toledo, Ohio, 43614, United States

  • Velindre Cancer Center

    Cardiff, CF14 2TL, United Kingdom

  • Virginia Cancer Specialists

    Fairfax, Virginia, 22031, United States

Conditions

Explore the condition pages connected to this study.