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New study reveals hidden toll of Cancer-Related weight loss on families

NCT ID NCT04090619

Knowledge-focused Sponsor: M.D. Anderson Cancer Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Aug 07, 2026 · Updated 3 times

Summary

This study looks at how often cancer patients experience cachexia (unintentional weight loss and appetite loss) and how this affects both patients and their primary caregivers emotionally. About 192 patients and their caregivers will fill out questionnaires during supportive care clinic visits. The goal is to better understand the frequency of cachexia and the psychological burden it creates, which could lead to improved support strategies.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could help develop better ways to support cancer patients and their families dealing with weight loss and stress.
What could go wrong
This is an observational study, not a treatment trial. It only measures what is already happening, so it cannot directly improve outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

192 people

The number who actually took part.

Started

Jun 2021

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with advanced cancer or relapsed hematological malignancies and their primary caregiver

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. \[Patient\] Patients visiting the Supportive Care Clinic (SCC) for a consultation or a follow up. 2. \[Patient\] Patients who can identify a primary caregiver. 3. \[Patient\] Diagnosis of advanced cancer defined as locally advanced, recurrent, or metastatic. 4. \[Patient\] Be able to read and speak English. 5. \[Patient\] 18 years of age or older. 6. \[Caregiver\] Be identified or self-identified as a primary caregiver of the patient. 7. \[Caregiver\] Provide informed consent 8. \[Caregiver\] Be able to read and speak English. 9. \[Caregiver\] 18 years of age or older. 10. \[Caregiver\] Caregivers who are not able to complete the questionnaire on the day of patients' SCC visit must be willing to engage in a telephone questionnaire with research staff within 60 days of the patient's enrollment. Exclusion Criteria: 1. \[Patient\] Refusal to participate in this study. This study requires both patient and caregiver enrollment. 2. \[Patient\] Patients with no caregiver or only paid caregivers. 3. \[Patient\] Patients with cognitive impairment as identified by research staff, treating physician or nurse (Memorial Delirium Assessment Scale score of \>/= 7). 4. \[Caregiver\] Refusal to participate in this study. This study requires both patient and caregiver enrollment. 5. \[Caregiver\] Not a primary caregiver or is a paid caregiver. 6. \[Caregiver\] Evidence of cognitive impairment, as determined based on orientation questions pertaining to the date, day of the week, time, and place

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Conditions

The condition(s) this trial relates to.

cancer leukemia lymphoma metastatic malignant neoplasm neoplasm Neoplasm Metastasis plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Advanced malignant solid neoplasm Caregiver Metastatic malignant solid neoplasm Recurrent leukemia Recurrent lymphoma Recurrent malignant solid neoplasm Recurrent plasma cell myeloma

Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.