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Why do people with hemophilia have fewer heart attacks? new study aims to find out

NCT ID NCT06706206

Knowledge-focused Sponsor: Oxford University Hospitals NHS Trust Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at why people with hemophilia (a bleeding disorder) are less likely to die from heart disease. Researchers will use a new, detailed CT scanner to compare heart artery health in 80 men aged 45+ with hemophilia to similar men without it. The goal is to understand how blood clotting affects heart attack risk, which could lead to new prevention strategies for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 80 people

The number the study aims to enrol. It can still change while the study runs.

Started

Feb 2025

Expected to finish

Jan 2032

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants must have a diagnosis of haemophilia A or B. Participants must be 45 years or older.

Ages

45 to 120 years

Sex

Male participants only

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Be willing and able to give informed consent for participation in the study. * Male, aged 45 years or above (no upper age limit). * Haemophilia A or B with Factor VIII/IX less than 40% (0.40 IU/ml). Exclusion Criteria: * Participants unable or unwilling to give informed consent. * Participants unable to understand the English language. * Participants unable or unwilling to attend for the necessary scans and investigations. * Patients with absolute contra-indications to CT imaging will be excluded from the study. This includes: * Any known contraindications to CT iodinated Contrast. * Significant renal impairment (eGFR \<30 ml/min). * Any other medical conditions which would influence the reliability of the study results determined by the investigators.

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder hemophilia hemophilia A hemophilia B

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiovascular diseases Haemophilia

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    1 site. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Oxford Haemophilia and Thrombosis Centre, Oxford University Hospitals NHS Foundation Trust

    RECRUITING

    Oxford, Oxfordshire, OX3 7HE, United Kingdom

    Contact Email: •••••@•••••

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