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Radiation boost may help CAR-T therapy fight bulky lymphoma

NCT ID NCT06104592

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 27 times

Summary

This study tests whether giving focused radiation to large tumors before CAR-T cell therapy can improve cancer control in people with aggressive large B-cell lymphoma. About 27 participants with tumors at least 5 cm will receive the combined treatment. The goal is to see if this approach delays cancer progression and reduces the chance of the cancer coming back at the treated sites.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact

    Contact

Conditions

Explore the condition pages connected to this study.