Radiation boost may help CAR-T therapy tackle bulky lymphoma
NCT ID NCT06104592
First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 26 times
Summary
This study tests whether giving targeted radiation to large tumors (at least 5 cm) before CAR-T cell therapy can improve cancer control in people with aggressive large B-cell lymphoma that has returned or not responded to treatment. About 27 participants will receive the radiation followed by standard CAR-T therapy. The goal is to see if this combination delays cancer progression and reduces the chance of the tumor coming back at the radiated site.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
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