Radiation boost may help CAR-T fight bulky lymphoma

NCT ID NCT06104592

Recruiting now Disease control Sponsor: H. Lee Moffitt Cancer Center and Research Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether giving focused radiation to large tumors before CAR-T cell therapy can help control aggressive large B-cell lymphoma that has come back or not responded to treatment. About 27 adults with tumors at least 5 cm will receive this combination. The goal is to see if the radiation improves how long the cancer stays away.

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Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma large B-cell lymphoma non-Hodgkin lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LARGE B-CELL LYMPHOMA RELAPSED NON-HODGKIN LYMPHOMA

Contacts and locations

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Study contacts

Contact

Email: •••••@•••••

Locations

Moffitt Cancer Center
RECRUITING

Tampa, Florida, 33612, United States

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