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Bone cell study explores direct effects of burosumab and vitamin d in kids with skull fusion

NCT ID NCT04159675

First seen Feb 06, 2026 · Last updated May 25, 2026 · Updated 13 times

Summary

This study looks at bone cells from children (ages 4 months to 18 years) who need surgery for craniosynostosis, a condition where skull bones fuse too early. Researchers want to see how burosumab and vitamin D directly affect these cells, especially in kids with hypophosphatemic rickets. The goal is to understand the treatments' impact on bone health, not to test a new therapy.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre de référence des craniosténoses et malformations cranio-faciales Service de neurochirurgie Pédiatrique

    RECRUITING

    Bron, 69500, France

    Contact

    Contact Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.