Cheek fat vs. palate tissue: which graft better protects dental implants in jawbone loss patients?
NCT ID NCT06968780
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests two surgical techniques—using a small piece of cheek fat or a rotated piece of palate tissue—to boost gum thickness and prevent implant exposure around zygomatic implants. Eight adults with severe upper jaw bone loss who need these special implants will be randomly assigned to one graft method. The goal is to see which approach leads to fewer gum problems and better long-term implant success.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 8 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jun 2025
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Patient of age 18 years or more, who can understand and sign an informed consent. 2. Patients with severely atrophic edentulous upper arch (Cawood \& Howell class IV, V, VI) that could not be restored by standard axial implants without augmentation. 3. Patients with severely atrophic edentulous upper arch (Bedrossian classification inadequate bone in zones II or III or all three zones) that could not be restored by standard axial implants without augmentation. 4. Good systemic health (ASA score I-II) 5. Highly motivated patients with good compliance to oral hygiene habits. Exclusion Criteria: 1. Patients with cardiovascular disease or pulmonary disease or medical systemic condition that does not permit the surgical procedure under general anesthesia (ASA III, IV, V and VI). 2. Patients with conditions contraindicating implant placement (e.g.: radiation to the head and neck, intra-venous bisphosphonates, uncontrolled Diabetes mellitus). 3. Heavy smokers. (\> 20 cigarettes daily) 4. Patient with psychiatric problems, severe bruxism, or other parafunctional habits. 5. Acute maxillary sinus infection or untreated maxillary sinus cyst. 6. Malignancy or pathology in Maxilla or Zygoma.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Cairo University
RECRUITINGCairo, Giza Governorate, 12613, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Could a Lab-Made collagen patch replace the painful palate graft for dental implants?
- Computer-Guided implant surgery aims to rebuild smiles for patients with severe jaw bone loss
- New study tests better gum coverage for dental implants in fragile jaws
- Metal vs plastic: which guide places cheekbone implants more accurately?
- Laser light may speed gum healing before dental bridges
- New bone shell technique could strengthen zygomatic implants