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New dosing study aims to improve vision control in AMD patients

NCT ID NCT04679935

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 34 times

Summary

This study tested two different dosing schedules of the drug brolucizumab in 52 adults aged 50 and older with age-related macular degeneration (AMD) who had not responded well to previous treatment. The goal was to see which schedule better maintains or improves vision over 52 weeks. Participants received injections of brolucizumab into the eye, and their vision was measured using standard eye charts.

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Contacts and locations

Locations

  • Novartis Investigative Site

    Regensburg, Bavaria, 93053, Germany

  • Novartis Investigative Site

    Frankfurt am Main, Hesse, 60549, Germany

  • Novartis Investigative Site

    Berlin, 13353, Germany

  • Novartis Investigative Site

    Bonn, 53105, Germany

  • Novartis Investigative Site

    Düsseldorf, 40225, Germany

  • Novartis Investigative Site

    Göttingen, 37075, Germany

  • Novartis Investigative Site

    Hanover, 30625, Germany

  • Novartis Investigative Site

    Homburg, 66421, Germany

  • Novartis Investigative Site

    Leipzig, 04103, Germany

  • Novartis Investigative Site

    Lübeck, 23538, Germany

  • Novartis Investigative Site

    Magdeburg, 39120, Germany

  • Novartis Investigative Site

    Mainz, 55131, Germany

  • Novartis Investigative Site

    Marburg, 35039, Germany

  • Novartis Investigative Site

    Münster, 48149, Germany

  • Novartis Investigative Site

    Neubrandenburg, 17036, Germany

  • Novartis Investigative Site

    Ulm, 89075, Germany

  • Novartis Investigative Site

    Lausanne, CHE, 1000, Switzerland

  • Novartis Investigative Site

    Bern, 3007, Switzerland

  • Novartis Investigative Site

    Zurich, 8063, Switzerland

Conditions

Explore the condition pages connected to this study.