New hope for rare blistering disease: drug may tame pemphigus without high steroid doses
NCT ID NCT06696716
First seen Nov 19, 2025 · Last updated May 17, 2026 · Updated 24 times
Summary
This study tests a new drug (ONO-4059) for people with pemphigus, a rare autoimmune disease that causes painful blisters on skin and mucous membranes. The trial includes 34 adults whose disease is not well controlled by steroids alone. Participants receive either ONO-4059 or a placebo, plus a low dose of steroids, to see if the drug can help achieve and maintain remission (no new blisters) for at least 8 weeks.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Ehime University Hospital
RECRUITINGEhime, Japan
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Fukushima Medical University Hospital
RECRUITINGFukushima, Japan
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Gunma University Hospital
RECRUITINGGunma, Japan
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Hokkaido University Hospital
RECRUITINGHokkaido, Japan
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Ichinomiya Municipal Hospital
RECRUITINGAichi, Japan
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Jichi Medical University Hospital
RECRUITINGTochigi, Japan
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Kagoshima University Hospital
RECRUITINGKagoshima, Japan
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Kawasaki Medical School Hospital
RECRUITINGOkayama, Japan
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Keio University Hospital
RECRUITINGTokyo, Japan
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Kindai university hospital
RECRUITINGOsaka, Japan
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Kumamoto University Hospital
RECRUITINGKumamoto, Japan
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Kurume University Hospital
RECRUITINGFukuoka, Japan
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Nagoya City University Hospital
RECRUITINGAichi, Japan
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Niigata University Medical & Dental Hospital
RECRUITINGNiigata, Japan
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Osaka Metropolitan University Hospital
RECRUITINGOsaka, Japan
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Saitama Medical Center
RECRUITINGSaitama, Japan
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Shiga University of Medical Science Hospital
RECRUITINGShiga, Japan
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St.Marianna University School of Medicine Hospital
RECRUITINGKanagawa, Japan
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Tokai University Hospital
RECRUITINGKanagawa, Japan
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Tokyo Medical and Dental University Hospital
RECRUITINGTokyo, Japan
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Tokyo Women'ｓ Medical University Hospital
RECRUITINGTokyo, Japan
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University Hospital Kyoto Prefectural University of Medicine
RECRUITINGKyoto, Japan
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University of the Ryukyus Hospital
RECRUITINGOkinawa, Japan
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Yamagata University Hospital
NOT_YET_RECRUITINGYamagata, Japan
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Yokohama City University Hospital
RECRUITINGKanagawa, Japan
Conditions
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