Can bright light ease Parkinson's sleep and mood troubles?
NCT ID NCT05524961
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether bright light therapy can help with sleepiness and mood problems in people with Parkinson's disease. 69 participants were randomly assigned to receive bright light, a placebo light, or an active control. The goal was to see if the therapy reduces daytime sleepiness and depressive symptoms.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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69 people
The number who actually took part.
- Started
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Dec 2022
- Finished
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Jan 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Idiopathic Parkinson's disease diagnosed by neurologist according to the UK Parkinson's Disease Society Brain Bank clinical diagnostic criteria 2. Capable to give informed consent 3. Maintained on stable dose of medications for Parkinson's disease/psychotropic drugs for at least four weeks prior to entry of the study 4. Score 14 or more on the Epworth Sleepiness Scale Exclusion Criteria: 1. A current or past history of manic or hypomanic episode, schizophrenia, mental retardation, or substance use disorder. (Subjects with depression or anxiety disorders will not be excluded) 2. Unstable medical or psychiatric condition 3. Presence of substantial suicidal risk as judged by the clinician and/or screening instruments 4. Presence of active psychotic symptoms that might impair the ability to consent or validity of the interview 5. Cognitive impairment with score of 19 or below by the Hong Kong version of Montreal Cognitive Assessment (HK-MoCA) 6. Contraindication to bright light therapy: history of light induced migraine. Epilepsy, current use of photosensitizing medications, presence of eye disease, e.g. retinal disease, severe cataract, glaucoma and blindness 7. Significant medical condition/ hearing impairment/ speech deficit lead to incapability in completing clinical interview 8. Regular shift worker or trans-meridian flight in the past three months 9. Enrolment in another clinical trial of an investigational medicinal product or device 10. Subjects who are on exogenous melatonin 11. Patients with deep brain stimulation (DBS) implant 12. Patients with known sleep disorders, eg. untreated severe sleep apnea, restless leg syndrome
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The Chinese University of Hong Kong
Hong Kong, Hong Kong
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Other studies related to the condition(s) this trial covers.
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