New shot aims to keep depression away longer
NCT ID NCT07412756
First seen Feb 17, 2026 · Last updated May 24, 2026 · Updated 4 times
Summary
This study tests whether adding a new drug called brenipatide to standard depression treatment can delay the return of major depressive symptoms. About 1000 adults with major depression who are already on stable medication will receive either brenipatide or a placebo as a shot, along with their usual care, for at least 12 months. The goal is to see if brenipatide helps people stay well longer.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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3rd People's Hospital of Huzhou
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NOT_YET_RECRUITINGLublin, 20-109, Poland
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NOT_YET_RECRUITINGTaoyuan, 333, Taiwan
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NOT_YET_RECRUITINGGwangju, 61469, South Korea
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NOT_YET_RECRUITINGTaichung, 402, Taiwan
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NOT_YET_RECRUITINGSioux Falls, South Dakota, 57104, United States
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NOT_YET_RECRUITINGZabrze, 41-807, Poland
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NOT_YET_RECRUITINGGuadalajara, 44650, Mexico
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NOT_YET_RECRUITINGMaringá, 87013-250, Brazil
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NOT_YET_RECRUITINGShavano Park, Texas, 78231, United States
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NOT_YET_RECRUITINGOttawa, K2J 3Z6, Canada
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NOT_YET_RECRUITINGExeter, EX2 5AF, United Kingdom
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NOT_YET_RECRUITINGHollywood, Florida, 33024, United States
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NOT_YET_RECRUITINGMiami Lakes, Florida, 33016-1518, United States
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NOT_YET_RECRUITINGBerlin, 10629, Germany
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NOT_YET_RECRUITINGKurume, 830-0033, Japan
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NOT_YET_RECRUITINGFukushima, 960-8053, Japan
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NOT_YET_RECRUITINGNatal, 59012-300, Brazil
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NOT_YET_RECRUITINGBarcelona, 08041, Spain
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NOT_YET_RECRUITINGMannheim, 68165, Germany
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RECRUITINGIndianapolis, Indiana, 46202, United States
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Jeju National University Hospital
NOT_YET_RECRUITINGJeju City, 63241, South Korea
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Jimbocho Mental Clinic
NOT_YET_RECRUITINGChiyoda City, 101-0051, Japan
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Keelung Chang Gung Memorial Hospital
NOT_YET_RECRUITINGKeelung, 204, Taiwan
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NOT_YET_RECRUITINGKawasaki, 214-0014, Japan
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NOT_YET_RECRUITINGKure, 737-0023, Japan
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RECRUITINGMiami Gardens, Florida, 33014, United States
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NOT_YET_RECRUITINGBrisbane, 4101, Australia
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Maynds Tower Mental Clinic
NOT_YET_RECRUITINGShibuya-ku, 151-0053, Japan
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Medical Care and Research SA de CV
NOT_YET_RECRUITINGMérida, 97070, Mexico
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Medical Concierge Centrum Medyczne
NOT_YET_RECRUITINGWarsaw, 02-798, Poland
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MentalMEDIC
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Miki Mental Clinic
NOT_YET_RECRUITINGYokohama, 220-0023, Japan
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Mildura Base Hospital
NOT_YET_RECRUITINGMildura, 3500, Australia
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Monzen-nakacho Mental Clinic
NOT_YET_RECRUITINGKōtō City, 135-0047, Japan
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Multidisciplinary Alfred Psychiatry Research Centre
NOT_YET_RECRUITINGMelbourne, 3004, Australia
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NOT_YET_RECRUITINGAthens, 124 62, Greece
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NOT_YET_RECRUITINGStavroupoli, 564 29, Greece
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NOT_YET_RECRUITINGLeszno, 64-100, Poland
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Nanko Kokorono Clinic
NOT_YET_RECRUITINGShirakawa, 961-0021, Japan
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National Cheng Kung University Hospital
NOT_YET_RECRUITINGTainan, 704, Taiwan
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National Taiwan University Hospital
NOT_YET_RECRUITINGTaipei, 10002, Taiwan
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NeuroCentrix
NOT_YET_RECRUITINGCarlton, 3053, Australia
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Neurozentrum Bielefeld
NOT_YET_RECRUITINGBielefeld, 33647, Germany
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Northwest Clinical Research Center
RECRUITINGBellevue, Washington, 98007, United States
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Optimal Research Sites
RECRUITINGOrange City, Florida, 32763, United States
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Papageorgiou General Hospital of Thessaloniki
NOT_YET_RECRUITINGThessaloniki, 564 29, Greece
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NOT_YET_RECRUITINGMelbourne, 3070, Australia
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NOT_YET_RECRUITINGBarcelona, 08003, Spain
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Peking University Sixth Hospital
NOT_YET_RECRUITINGHaidian District, 100191, China
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NOT_YET_RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
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Pharmakologisches Studienzentrum Chemnitz
NOT_YET_RECRUITINGChemnitz, 09111, Germany
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Pharmasite Research, Inc.
RECRUITINGBaltimore, Maryland, 21208, United States
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Podlaskie Centrum Psychogeriatrii
NOT_YET_RECRUITINGBialystok, 15-756, Poland
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Premier Clinical Trial Network
NOT_YET_RECRUITINGHamilton, L8L 5G4, Canada
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Private Practice - Dr. Małgorzata Wojtanowska-Bogacka
NOT_YET_RECRUITINGPoznan, 60-192, Poland
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Queen Elizabeth University Hospital
NOT_YET_RECRUITINGGlasgow, G51 4TF, United Kingdom
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Queen's Medical Centre, Nottingham University Hospitals
NOT_YET_RECRUITINGNottingham, NG7 2UH, United Kingdom
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Rainbow and Sea Hospital
NOT_YET_RECRUITINGKaratsu, 847-0031, Japan
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Re:Cognition Health
NOT_YET_RECRUITINGFairfax, Virginia, 22031, United States
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Re:Cognition Health - Fort Worth
RECRUITINGFort Worth, Texas, 76104, United States
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Renmin Hospital of Wuhan University
NOT_YET_RECRUITINGWuhan, 430060, China
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Richmond Clinical Trials
NOT_YET_RECRUITINGRichmond, V6V 2L1, Canada
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Ruschel Medicina e Pesquisa Clínica
NOT_YET_RECRUITINGRio de Janeiro, 22270-060, Brazil
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SCB Research Center
NOT_YET_RECRUITINGBayamón, 00961, Puerto Rico
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Sakurazaka Clinic SophyAnce
NOT_YET_RECRUITINGTokyo, 106-0032, Japan
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Samsung Medical Center
NOT_YET_RECRUITINGSeoul, 06351, South Korea
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Sangenjaya Shinkeika Shinryonaika Clinic
NOT_YET_RECRUITINGSetagaya City, 154-0004, Japan
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Scientia Investigacion Clinica S.C.
NOT_YET_RECRUITINGChihuahua City, 31207, Mexico
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Senzoku Psychosomatic Medicine Clinic
NOT_YET_RECRUITINGMeguro-ku, 152-0012, Japan
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Seoul National University Hospital
NOT_YET_RECRUITINGSeoul, 03080, South Korea
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Severance Hospital, Yonsei University Health System
NOT_YET_RECRUITINGSeoul, 03722, South Korea
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Shandong Daizhuang Hospital
NOT_YET_RECRUITINGJining, 272051, China
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Shanghai Mental Health Center
NOT_YET_RECRUITINGShanghai, 200030, China
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Shioiri Mental Clinic
NOT_YET_RECRUITINGYokosuka, 238-0042, Japan
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Somni bene
NOT_YET_RECRUITINGSchwerin, 19053, Germany
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St Bartholomew's Medical Centre
NOT_YET_RECRUITINGOxford, OX4 1XB, United Kingdom
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Suburban Research Associates
RECRUITINGMedia, Pennsylvania, 19063, United States
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Suizenji Life Clinic
NOT_YET_RECRUITINGKumamoto, 862-0956, Japan
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Summit Headlands
NOT_YET_RECRUITINGPortland, Oregon, 97210, United States
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Suzhou Guangji Hospital
NOT_YET_RECRUITINGSuzhou, 215003, China
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Taipei Medical University Hospital
NOT_YET_RECRUITINGTaipei, 110, Taiwan
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Taipei Veterans General Hospital
NOT_YET_RECRUITINGTaipei, 11217, Taiwan
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The Affilicated Kangning Hospital of Ningbo University
NOT_YET_RECRUITINGNingbo, 315201, China
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The Catholic Univ. of Korea Seoul St. Mary's Hospital
NOT_YET_RECRUITINGSeoul, 06591, South Korea
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The First Affiliated Hospital of Nanchang University
NOT_YET_RECRUITINGNanchang, 330006, China
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The First Hospital of Hebei Medical University
NOT_YET_RECRUITINGShijiazhuang, 050031, China
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The Fourth People's Hospital of Chengdu
NOT_YET_RECRUITINGChengdu, 610036, China
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The Maudsley Hospital
NOT_YET_RECRUITINGLondon, SE5 8AZ, United Kingdom
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The Second People's Hospital of Hunan Province
NOT_YET_RECRUITINGChangsha, 410007, China
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Tianjin Anding Hospital
NOT_YET_RECRUITINGTianjin, 300022, China
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Toowoomba Hospital
NOT_YET_RECRUITINGToowoomba, 4350, Australia
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Trial Tech
NOT_YET_RECRUITINGCuritiba, 80240-280, Brazil
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Uematsu Mental Clinic
NOT_YET_RECRUITINGChikugo, 833-0041, Japan
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University of the Ryukyus Hospital
NOT_YET_RECRUITINGGinowan, 901-2725, Japan
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Universitätsklinikum Aachen
NOT_YET_RECRUITINGAachen, 52074, Germany
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Universitätsmedizin Johannes Gutenberg Universität Mainz
NOT_YET_RECRUITINGMainz, 55131, Germany
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Vector Clinical Trials
RECRUITINGLas Vegas, Nevada, 89128, United States
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Warneford Hospital
NOT_YET_RECRUITINGOxford, OX3 7JX, United Kingdom
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Westmead Hospital
NOT_YET_RECRUITINGWestmead, 2145, Australia
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Winterberry Research Inc.
NOT_YET_RECRUITINGHamilton, L8J 0B6, Canada
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Woodstock Bower Surgery
NOT_YET_RECRUITINGRotherham, S61 1AH, United Kingdom
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Wuxi Mental Health Center
NOT_YET_RECRUITINGWuxi, 214151, China
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Xi An Mental Health Center
NOT_YET_RECRUITINGXi'an, 710061, China
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Xianyang Hospital of Yan'an University
NOT_YET_RECRUITINGXianyang, 712000, China
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Yale University School of Medicine
NOT_YET_RECRUITINGNew Haven, Connecticut, 06519, United States
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Yamagata Sakuracho Hospital
NOT_YET_RECRUITINGYamagata, 990-0045, Japan
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Yuge Hospital
NOT_YET_RECRUITINGKumamoto, 861-8002, Japan
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Yutaka Clinic
NOT_YET_RECRUITINGSagamihara, 252-0303, Japan
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ZNS Siegen
NOT_YET_RECRUITINGSiegen, 57076, Germany
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Zhumadian Psychiatric Hospital
NOT_YET_RECRUITINGZhumadian, 463000, China
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Conditions
Explore the condition pages connected to this study.