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Laughter may be the best medicine for COPD breathlessness

NCT ID NCT05997550

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether pursed lip breathing exercises and laughter therapy can reduce shortness of breath, improve health status, and lower care dependence in people with chronic obstructive pulmonary disease (COPD). 63 adults with COPD were split into three groups: one did breathing exercises, one did laughter therapy, and one received standard education. The interventions lasted 8 weeks, and symptoms were measured at 4, 8, and 12 weeks.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
pursed lip breathing exercise and laughter therapy
What this could lead to
If it works, this could offer simple, drug-free ways to help people with COPD feel less breathless and more independent.
What could go wrong
This is a small, completed study with only 63 participants. The results may not apply to everyone with COPD, and the benefits might be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

63 people

The number who actually took part.

Started

Aug 2022

Finished

Oct 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Those aged 40 and over, * He was diagnosed with COPD as a result of medical history, physical examination and pulmonary function tests, and his CAT score is 10 and above according to the COPD Unified Assessment\* of the GOLD guide; In Group B and D (1), * There is no diagnosis of a disease that may affect the cognitive state, * Not having a diagnosis of a physical or mental illness that will prevent communication, and able to use a telephone. * Individuals who agree to participate in the research are included in the study Non-Inclusion Criteria: Those who have difficulty in verbal communication (intubation, tracheostomy, delirium, etc.) * With a CAT score of less than 10 and in Groups A and C according to the COPD Combined Assessment\* of the GOLD guide, * Having a disorder that disrupts the cognitive process such as schizophrenia or dementia * Alcohol, substance addiction, * Laughter therapy was not deemed appropriate due to the diagnosis of abdominal surgery, uncontrolled hypertension, glaucoma, abdominal hernia, epilepsy in the last three months, * Using complementary and integrative treatments such as acupuncture, meditation, yoga, massage, relaxation exercises, * Patients who do not agree to participate in the study are excluded from the study. Exclusion criteria * Not complying with pursed lip breathing exercise and laughter therapy and program, * Developing a disease that may affect the health status or a condition requiring hospitalization (COPD exacerbation, etc.) during the 12-week period during which the research will take place, * Changes in bronchodilator and oxygen therapy regimens, * A situation that is not suitable for laughter therapy due to the diagnosis of surgery in the abdominal region, uncontrollable hypertension, glaucoma, abdominal hernia, epilepsy, * Patients who want to withdraw from the study are excluded from the study.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Bilkent City Hospital

    Ankara, Çamlıca Mahallesi, 06520, Turkey (Türkiye)

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