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Can a deeper nerve block ease pain after breast surgery?

NCT ID NCT07724678

Symptom relief Sponsor: SBU Ankara Egitim ve Arastirma Hastanesi Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 24, 2026 · Last updated Sep 04, 2026 · Updated 1 time

Summary

This trial tests two types of nerve blocks for pain after breast cancer surgery. One method targets a deeper layer of muscle, while the other combines both superficial and deep layers. The goal is to see which approach better reduces pain, cuts down on opioid use, and improves comfort for women undergoing mastectomy or breast-conserving surgery.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a combination of superficial and deep serratus anterior plane block (a nerve block) versus deep serratus anterior plane block alone
What this could lead to
If one nerve block method proves better, it could lead to less pain and less need for strong painkillers after breast surgery.
What could go wrong
This is a small, single-center trial, so results may not apply to all patients. Nerve blocks carry small risks like bleeding or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

76 people

The number who actually took part.

Started

Apr 2025

Finished

May 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients undergoing elective modified radical mastectomy or breast-conserving surgery at SBU Ankara Egitim ve Arastirma Hastanesi

Ages

18 to 80 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Patients aged 18-80 years. Female patients with ASA physical status I, II, or III. Patients scheduled for elective modified radical mastectomy or breast-conserving surgery. Patients who provided written and verbal informed consent. Exclusion Criteria: Patients with ASA physical status IV-V. Patients with a BMI ≥ 35 kg/m². Patients with chronic pain, opioid/substance addiction, or long-term analgesic use. Patients requiring emergency surgery. Pregnant patients. Known allergy to local anesthetics. Severe cardiovascular, cerebrovascular, liver, or renal disease. History of coagulopathy. Infection at the injection site or systemic infection. Patients who refuse the regional anesthesia technique, cannot speak the official language, or have mental disabilities/inability to cooperate. Patients with a history of previous breast surgery or those scheduled for bilateral operations.

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Conditions

The condition(s) this trial relates to.

agnosia breast cancer breast neoplasm Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Breast cancer Pain management after surgery Postoperative pain

Contacts and locations

Locations

  • Ankara Training and Research Hospital

    Altındağ, Ankara, 00000, Turkey (Türkiye)

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