Could a quick MRI catch more breast cancers in black women?
NCT ID NCT04854304
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study is testing whether a fast breast MRI can find cancers that mammograms miss in Black women with dense breast tissue. About 500 African American women who recently had a normal mammogram will get an additional abbreviated MRI. Researchers want to see if this extra scan detects more cancers and reduces false negatives, while also comparing results to similar studies in white women.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Fast breast MRI (diagnostic test)
- What this could lead to
- If successful, this could show that adding fast breast MRI helps find breast cancers earlier in Black women with dense breasts, potentially reducing disparities in outcomes.
- What could go wrong
- This is an early-stage study with 500 participants, so results may not apply to all women. Fast MRI may also lead to false alarms or unnecessary biopsies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 500 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2021
- Expected to finish
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Jul 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Women who have no personal history and no family history of Breast Cancer.
- Ages
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40 to 75 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. African American female 2. Negative DBT examination within eleven months prior to recruitment 3. Heterogeneoulsy and Extremely breast densities 4. Clinically asymptomatic- no palpable masses or focal thickening, etc. Exclusion Criteria: 1. Patients who are pregnant and lactating 2. Patient who have not had a mammogram (DBT) in the past 11months 3. Patients who are unwilling or unable to provide written informed consent 4. Patients symptomatic for breast disease (e.g. experiencing discharge, lumps, ect.) 5. Recent breast surgery in the past 2 years including breast enhancements (e.g. implants or injections) 6. Patients who are unable to received an MRI with Gadolinium contrast 7. Patients who have not had an MRI of the breast with the past year
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
UPENN
Philadelphia, Pennsylvania, 19104, United States
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Other studies related to the condition(s) this trial covers.
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