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Glow-in-the-Dark dye could help breast cancer patients avoid second surgery

NCT ID NCT07140965

First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 25 times

Summary

This study tests whether a special fluorescent dye and imaging system can help surgeons see and remove all cancer during breast-conserving surgery. The goal is to reduce the chance that cancer cells are left behind, which often requires a second operation. About 175 women with breast cancer will take part. The trial is currently on hold.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • MD Anderson Cancer Center

    Houston, Texas, 77030, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Pegulicianine (fluorescent dye) used with the Lumicell Direct Visualization System

What this could lead to

If successful, this approach could help surgeons remove all cancer in one operation, reducing the need for a second surgery and improving outcomes for breast cancer patients.

What could go wrong

This trial is currently suspended, and it is a relatively small, early-stage study focused on safety and feasibility. The technology may not work as hoped or may not reduce second surgeries significantly.

Conditions

The condition(s) this trial relates to.

breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.