Could a Risk-Based screening schedule replace standard mammograms?
NCT ID NCT06060938
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study involves 2,200 women aged 50–67 to see if personalized mammography screening, based on genetic and lifestyle risk factors, is safe and acceptable. Half the women receive standard biennial mammograms, while the other half get a risk assessment and a tailored screening schedule (every 1–4 years). The main goal is to measure how many low-risk women choose to stick with the standard 2-year interval instead of the recommended 4-year interval.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 2,200 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2024
- Expected to finish
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Dec 2034
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 to 67 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female sex * Age between 50 and 67 (both included) years. * Invited for the regular breast cancer mammography screening program * Signed an informed consent Exclusion Criteria: * Personal history of breast cancer * Known high risk of breast cancer * Ethnic origin, for which the risk model has not been validated.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Dept. of Breast Examinations, Herlev Gentofte Hospital, Copenhagen University Hospital
Gentofte Municipality, 2900, Denmark
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