Can sound waves replace needles for breast cancer diagnosis?
NCT ID NCT04721886
First seen Apr 11, 2026
Summary
This study tested whether contrast-enhanced ultrasound (CEUS) can estimate the pressure inside breast tumors without using a needle. Twenty-five women scheduled for breast biopsy received an IV contrast agent and underwent ultrasound imaging. The goal was to see if the ultrasound pressure readings matched direct needle measurements, potentially offering a less invasive diagnostic option.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
-
Thomas Jefferson University Hospital
Philadelphia, Pennsylvania, 19107, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Perflutren lipid microspheres (Definity) given intravenously
What this could lead to
If successful, this could lead to a noninvasive way to measure tumor pressure, helping doctors diagnose breast cancer without needles.
What could go wrong
This is a very early, small study (25 people) testing a method, not a treatment. It may not prove accurate enough for routine use.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.