Can Pre-Treatment exercise ease breast cancer side effects?
NCT ID NCT06081127
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether physical therapy and education before breast cancer treatment can help prevent or reduce side effects like joint pain, muscle weakness, and fatigue. 75 newly diagnosed patients were randomly assigned to either the MOve-ABC program (physical therapy, home exercises, and self-management education) or enhanced usual care. The goal was to see if the program is feasible and may improve physical function and self-management.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- physical therapy and patient education program (MOve-ABC)
- What this could lead to
- If it works, this approach could help breast cancer patients better manage side effects like pain and fatigue, improving their daily function during and after treatment.
- What could go wrong
- This is a small pilot study (75 people) testing feasibility, not effectiveness. The results may not apply to all patients, and the program may not show clear benefits in a larger trial.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
75 people
The number who actually took part.
- Started
-
Nov 2023
- Finished
-
May 2025
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 years and older
- Sex
-
Female participants only
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with newly diagnosed Breast Cancer (BC) (stages 0-4) deemed eligible by the oncology physician team to undergo intent-to-cure treatment * Patients must have an Eastern Cooperative Oncology Group (ECOG) Performance Scale score of 0 (Fully active, able to carry on all pre-disease performance without restriction), 1 (Restricted in physically strenuous activity but ambulatory and able to carry out work of a light or sedentary nature, e.g., light house- work, office work); or 2 (Ambulatory and capable of all self-care but unable to carry out any work activities; up and about more than 50% of waking hours) * Patients must be Female \[Note: Males are not included as BC in males is less than 1% of all cases\] * Patients must be English speaking * Patients must be age ≥ 18 years * Patients must have regular access to a mobile phone that can receive text messages and phone calls * Patients must have the ability to understand and the willingness to sign a written informed consent document prior to registration on study Exclusion Criteria: * Patient with any prior malignancy (except non-melanoma skin) * Patients with an ECOG Performance Scale score of 3 (Capable of only limited self-care; confined to bed or chair more than 50% of waking hours), 4 (Completely disabled; cannot carry on any self-care; totally confined to bed or chair) or 5 (dead) * History of pre-existing upper extremity functional impairment, lymphedema, central nervous system damage, other systemic medical condition (e.g. fibromyalgia, rheumatoid arthritis, diabetes) * Actively receiving physical therapy at the time of recruitment and baseline measurement * Patients with brain metastasis with adverse events attributable to the metastasis ≥ grade 3 * Patients who are pregnant or lactating * Patients with any issue that would limit their ability to comply with study requirements
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Breast cancer are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Northwestern University
Chicago, Illinois, 60611, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a common steroid shield breast cancer patients from a dangerous drug side effect?
- Tiny magnetic seeds could guide surgeons to the right lymph node
- New PET tracer aims to light up hidden cancer targets
- Gut bacteria supplement tested against chemo hair loss
- Can a mindfulness program boost Self-Compassion in breast cancer survivors?
- Can a Decades-Old Anti-Inflammatory drug quiet the joint pain that drives women off breast cancer therapy?