New hope: Pre-Surgery combo shrinks breast tumors, spares healthy tissue
NCT ID NCT01750073
First seen Nov 18, 2025 · Last updated May 01, 2026 · Updated 24 times
Summary
This study tests whether giving chemotherapy (paclitaxel and cyclophosphamide) with or without the targeted drug trastuzumab before surgery can shrink breast tumors and reduce the amount of healthy tissue that needs to be removed. It includes 92 women with early-stage or locally advanced breast cancer that is either HER2-positive or HER2-negative. The main goals are to check side effects and see how many patients have no cancer left at surgery.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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CHI Health Saint Francis
Grand Island, Nebraska, 68803, United States
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Nebraska Medicine-Bellevue
Bellevue, Nebraska, 68123, United States
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Nebraska Medicine-Village Pointe Cancer Center
Omaha, Nebraska, 68118, United States
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University of Nebraska Medical Center
Omaha, Nebraska, 68198, United States
Conditions
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