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5,000+ breast cancer cases analyzed to improve future treatment

NCT ID NCT07521397

Knowledge-focused Sponsor: Hellenic Cooperative Oncology Group Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study combined data from over 5,300 people with early-stage breast cancer who received a specific type of chemotherapy. Researchers wanted to see how long patients lived without the cancer coming back and what side effects they had. The goal is to learn from past treatments to help doctors make better decisions for future patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

5,358 people

The number who actually took part.

Started

Dec 1996

Finished

Jul 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population includes 5,378 patients with early-stage, surgically resected breast cancer of high or intermediate risk who participated in seven observational studies (three phase III trials and four observational studies) conducted by the Hellenic Cooperative Oncology Group (HeCOG). All patients received adjuvant dose-dense sequential chemotherapy (ddsc), and individual patient-level data were available for demographic, pathological, treatment, and outcome variables.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients with early-stage, surgically resected breast cancer (high or intermediate risk), randomized to receive adjuvant or neoadjuvant dose-dense sequential chemotherapy. Exclusion Criteria: * Patients with metastatic or locally advanced breast cancer at initial diagnosis. Patients who did not receive dose-dense sequential chemotherapy.

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Conditions

The condition(s) this trial relates to.

breast cancer breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Adjuvant chemotherapy Breast cancer Early-stage breast cancer Overall survival Prognosis breast cancer

Contacts and locations

Locations

  • Study site

    Athens, 11526, Greece

More trials for these conditions

Other studies related to the condition(s) this trial covers.