Chemo may age organs faster: new study investigates
NCT ID NCT06789653
First seen Jun 24, 2026 · Last updated Aug 19, 2026 · Updated 3 times
Summary
This study looks at whether chemotherapy speeds up aging in the body's organs. Researchers will take blood samples from 80 women with early-stage breast cancer before and after treatment to measure markers of cellular aging. The goal is to find out if these markers can predict who might have long-term side effects like heart problems or nerve damage.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help identify which breast cancer patients are at highest risk for long-term side effects from chemotherapy, such as heart problems or nerve damage.
- What could go wrong
- This is an early observational study with only 80 participants, so results may not apply to all patients. It measures biological markers, not direct health outcomes, so it may not lead to changes in treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 80 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2024
- Expected to finish
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Nov 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with breast carcinoma were treated at the study site. Groups will be stratified to ensure that those receiving anthracycline-containing regimens are well-represented and into three different age groups: \< 50, 50 to 65, and 66 years and older
- Ages
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22 to 66 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥22years and \<66 years * Diagnosed with early-stage breast cancer (The American Joint Committee on Cancer stages I-III). * Understand and read English. * Receive care at the study site. * Able to understand and participate in study procedures for length of study. Exclusion Criteria: * Unable to provide consent, unable to communicate verbally. * Unable to understand or read English. * Enrolled in hospice care.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of North Carolina
RECRUITINGChapel Hill, North Carolina, 27599, United States
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- Can a Decades-Old Anti-Inflammatory drug quiet the joint pain that drives women off breast cancer therapy?