Early trial tests repurposed leukemia pill for tough brain tumors in kids and young adults
NCT ID NCT07039760
Summary
This early study aims to see if a drug called asciminib, which is approved for leukemia, can get into brain tumors at high enough levels to potentially help. Researchers will test asciminib alone and combined with sildenafil (Viagra) in 12 young patients (ages 6-25) with recurrent brain tumors that can be surgically removed. The main goal is to measure how much of the drug reaches the tumor compared to the blood, to see if it's a promising approach worth further study.
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Washington University School of Medicine/St. Louis Children's Hospital
St Louis, Missouri, 63110, United States
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