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Love on the brain: study reveals how Couples' minds connect

NCT ID NCT07385027

Knowledge-focused Sponsor: Spaulding Rehabilitation Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study looks at how the brains of romantic partners communicate compared to strangers. Using a technique called hyperscanning, researchers will record brain activity from two people at the same time, both in person and remotely. The goal is to understand what factors, like attachment style or age, influence brain-to-brain connections. Forty healthy couples will participate in EEG scans and complete tasks involving pain and communication.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2025

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Twenty healthy control romantic pair dyads will be recruited for this study, for a total of 40 participants. Male and female participants, aged 20-60, will be recruited.

Ages

20 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria 1. Healthy volunteers in a romantic partnership for at least 6 months. 2. 20-60 years of age 3. Ability to fully understand and consent to study procedures. 4. Fluent in English 5. Are on stable doses of medication for 30 days prior to entering the study and agree not to change medications or dosages during the trial. Exclusion Criteria: 1. Presence of any contraindications to EEG scanning. 2. Illicit drug or opioid use. 3. Epilepsy, seizures provoked by lights or a prior history of seizures. 4. Presence of any illness that is judged to interfere with the trial. For example: severe psychiatric disorders according to the DSM-IV manual. 5. Current chronic pain conditions. 6. Unwillingness to be audio recorded. 7. Unwillingness to receive brief experimental pain on the lower left leg. 8. Unwillingness to withhold from consuming marijuana 48 hours prior to scans. 9. Unwillingness to withhold from consuming nicotine 4 hours prior to scans. 10. Any impairment, activity, or situation that in the judgment of the Study Coordinator or Principal Investigator would prevent satisfactory completion of the study protocol.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Brain to brain communication

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Spaulding Rehabilitation Hospital

    RECRUITING

    Charlestown, Massachusetts, 02129, United States