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Can a stress hormone explain alcohol relapse?

NCT ID NCT07612631

First seen May 29, 2026 · Last updated Jun 20, 2026 · Updated 4 times

Summary

This study uses brain scans to see how stress-related proteins change in heavy drinkers compared to healthy people. Researchers give a stress hormone (hydrocortisone) and then scan the brain to measure these proteins. The goal is to understand if these proteins play a role in relapse. About 90 people will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

hydrocortisone

What this could lead to

If successful, this could help explain why some heavy drinkers relapse, pointing toward future stress-focused treatments.

What could go wrong

This is a very early, small imaging study, not a treatment trial. It may not lead to any direct benefit for participants.

Conditions

The condition(s) this trial relates to.

alcohol abuse

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.