Rajesh Narendran

Researchers are using PET scans to measure mitochondrial Complex-I and glucose metabolism in the brains of people with alcohol use disorder and healthy volunteers. The study aims to see whether these markers differ between the two groups and whether they relate to alcohol craving…

This study uses a special PET imaging tracer to measure how much energy the brain uses in people with cocaine use disorder compared to healthy controls. The goal is to see if energy use in key brain regions, like the orbitofrontal cortex and midbrain, differs in addiction. This c…

This study uses brain scans (PET) to measure how much dopamine is released after a low dose of amphetamine in people with cocaine use disorder. Researchers want to understand brain changes linked to addiction. About 30 adults aged 18-55 with cocaine use disorder will participate.…

This study uses brain scans to see how stress hormones interact with certain brain receptors in people with cocaine use disorder. Researchers will compare 80 adults with and without the disorder to understand these interactions and whether they predict relapse. The goal is to lea…

This study uses brain scans to see how stress-related proteins change in heavy drinkers compared to healthy people. Researchers give a stress hormone (hydrocortisone) and then scan the brain to measure these proteins. The goal is to understand if these proteins play a role in rel…