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Brain zaps may help teens with chronic pain get more from rehab

NCT ID NCT04561401

Symptom relief Sponsor: University of Calgary Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding a non-invasive brain stimulation technique called rTMS to a three-week intensive pain rehabilitation program can help youth aged 10-18 with severe chronic pain. The goal is to see if the stimulation can reduce pain and improve daily function, mood, and brain activity. It's a small early trial with 25 participants, so results will be preliminary.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
repeated transcranial magnetic stimulation (rTMS)
What this could lead to
If it works, this could point toward a new way to ease chronic pain and improve daily life for youth who haven't gotten relief from other treatments.
What could go wrong
This is a very small, early study with only 25 participants and no control group. The results may not apply to all youth with chronic pain, and the benefits might be modest.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 25 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2020

Expected to finish

Apr 2028

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

10 to 18 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Between the ages of 10-18 years * Patient has had the appropriate medical work-up * Participation in accessible, evidenced based pain therapies has not demonstrated return to functional goals * Pain is significantly impacting the patient's life and they are not meeting their functional goals in areas of life, which may include: physical function, sleep, self-care, school attendance/academic performance, social function, recreational engagement, and mood * Patient and family agree and understand that an active, self-management approach to functional restoration is the mainstay of treatment in the IPRP Exclusion Criteria: * Significant developmental delay or brain injury * Functional neurological disorder/conversion disorder * Youth who require opioid weaning * Extensive medical needs and/or untreated psychiatric illness that would impede a rehabilitative approach to care.

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic pain

Contacts and locations

Locations

  • University of Calgary

    Calgary, Alberta, T3B 6A8, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.