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New brain zapping technique aims to lift severe depression faster

NCT ID NCT07329153

First seen Jan 11, 2026 · Last updated May 20, 2026 · Updated 25 times

Summary

This study tests a quick, non-invasive brain stimulation method called accelerated intermittent theta-burst stimulation (aiTBS) for people with depression that hasn't improved with standard treatments. About 247 adults aged 18-65 will be randomly assigned to receive either aiTBS with precise brain targeting (neuronavigation), aiTBS without it, or a sham (fake) procedure. The goal is to see if these approaches can safely reduce depression symptoms.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Cornell University

    New York, New York, 10065, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of California at San Diego (UCSD)

    San Diego, California, 92127, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Texas Southwestern Medical Center

    Dallas, Texas, 75390, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.