Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Cure My Disease

Don't miss your cure!

 Log in / Sign up

Can brain signals predict freezing episodes in Parkinson's?

NCT ID NCT07748962

Knowledge-focused Sponsor: The Cleveland Clinic Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This study investigates how brain signals relate to freezing of gait and balance problems in people with Parkinson's disease. Participants, who already have a deep brain stimulation (DBS) device, will walk in a virtual reality home-like environment while their brain activity is recorded. Researchers will test different DBS settings to see how they affect walking and freezing episodes. The goal is to better understand the brain mechanisms behind these symptoms and potentially improve DBS therapy.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Deep brain stimulation (DBS) with temporarily adjusted settings
What this could lead to
If successful, this could help tailor DBS settings to better prevent freezing of gait and improve balance in Parkinson's disease.
What could go wrong
This is a very small, early-stage study (5 participants) focused on understanding brain signals, not a treatment trial. Results may not apply to all patients, and temporary DBS adjustments carry risks like worsening symptoms.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 5 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * You have been diagnosed with Parkinson's disease * You already have a deep brain stimulation (DBS) device implanted as part of your medical care - specifically, the Medtronic Percept DBS device * Your DBS settings have been stable for at least 3 months * You experience freezing of gait (sudden inability to move your feet when trying to walk) * You are able to walk on your own for at least 10 minutes without assistance * You are willing to temporarily stop your Parkinson's medications and have your DBS settings adjusted for study testing * You are able to understand the study and provide consent to participate Exclusion Criteria: * You have a neurological condition other than Parkinson's disease (such as stroke or multiple sclerosis) * You have been diagnosed with dementia or have difficulty understanding the study or giving consent * You currently have alcohol or substance abuse problems * You have hearing or vision problems that would make it difficult to use a virtual reality headset * You have any medical or mental health condition that, in the opinion of the study doctor, would make it unsafe or difficult for you to participate

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Freezing of gait are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Freezing of gait Parkinson disease

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.