Brain surgery patients play theremin to unlock secrets of learning
NCT ID NCT05688683
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how the brain learns to control sound by having patients play a theremin-like instrument during awake brain surgery. Researchers will record brain activity directly from the surface of the brain to understand sensorimotor learning. The study involves 50 people with epilepsy or brain tumors who are already scheduled for surgery. This is not a treatment but aims to gather knowledge about brain function.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could improve our understanding of how the brain learns fine motor skills, potentially aiding rehabilitation after brain injury.
- What could go wrong
- This is a small, early-stage observational study focused on brain activity recording, not a treatment. Results may not directly translate to therapies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 50 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2023
- Expected to finish
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Mar 2028
An estimate. End dates often move.
- Lead sponsor
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A research network
The lead sponsor is a research network or cooperative group.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patient benefiting from an intracranial brain recording during a programmed surgery for epilepsy or cerebral tumor resection in awake condition.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Benefiting from an intracranial brain recording during a programmed surgery in awake condition. Exclusion Criteria: * Patient with complete deafness * Patient with a disorder or impairment that does not allow him/her to perform the experimental task according to the investigator's judgment
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Fondation Adolphe de Rothschild
RECRUITINGParis, 75010, France
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Other studies related to the condition(s) this trial covers.
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- Can video games rewire young brains after injury?
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- Epilepsy drug candidate put to the test in healthy volunteers