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Brain receptor may unlock how sleep therapy fights depression

NCT ID NCT07076342

First seen Feb 18, 2026 · Last updated May 19, 2026 · Updated 10 times

Summary

This study looks at how a brain protein called mGluR5 might help explain why cognitive behavioral therapy for insomnia (CBT-I) can also improve depression. Researchers will measure changes in this receptor and sleep patterns in 42 adults with major depression and insomnia. The goal is to understand the brain mechanism, not to test a new treatment.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Stony Brook University: Dept of Psychiatry

    RECRUITING

    Stony Brook, New York, 11794, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.