New hope for Radiation-Damaged brains: drug trial challenges steroid standard
NCT ID NCT06888817
Summary
This study compares two treatments for brain swelling (radiation necrosis) that can occur after radiation therapy for brain tumors or metastases. 408 patients will receive either the standard steroid treatment (dexamethasone) or an alternative drug called bevacizumab, given intravenously every three weeks. The goal is to see which treatment better controls symptoms while allowing patients to use less steroids, which often cause significant side effects.
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Contacts and locations
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Study contacts
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Locations
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Amsterdam University Medical Centers, location VUmc and AMC
RECRUITINGAmsterdam, Netherlands
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Haaglanden Medical Center
RECRUITINGThe Hague, 2262 BA Leidschendam, Netherlands
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Leiden University Medical Center
RECRUITINGLeiden, 2333 ZA Leiden, Netherlands
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Netherlands Cancer Institute - Antoni van Leeuwenhoek
RECRUITINGAmsterdam, 1066 CX Amsterdam, Netherlands
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University Medical Center Utrecht
RECRUITINGUtrecht, 3584 CX Utrecht, Netherlands
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Conditions
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