Which Brain-Saving technique works best in aortic tear emergencies?
NCT ID NCT07043777
First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time
Summary
This study looks at two ways to keep the brain supplied with blood during emergency surgery for a life-threatening tear in the aorta (the main artery from the heart). One method delivers blood to all three major arteries in the head, while the other uses only the right armpit artery. Researchers reviewed records of 201 adults who had this surgery at one hospital between 2021 and 2025 to see which approach led to fewer strokes and better survival.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If one method proves safer, it could guide surgeons on the best way to protect the brain during this high-risk emergency surgery.
- What could go wrong
- This is a small, single-hospital review, not a randomized trial. The two groups were treated by different surgeons, so results may be due to skill rather than the method itself.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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201 people
The number who actually took part.
- Started
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Jan 2021
- Finished
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Jun 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Consecutive adult patients who underwent emergency total arch replacement for acute type A aortic dissection at China Medical University Hospital, Taichung, Taiwan, between 1 January 2021 and 30 April 2025. The analytic population was restricted to patients who received either direct three-vessel antegrade cerebral perfusion (MACP) or unilateral right axillary antegrade cerebral perfusion (uACP).
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18 years or older. * Patients who underwent emergency total arch replacement for acute type A aortic dissection at China Medical University Hospital between 1 January 2021 and 30 April 2025. * Patients who received either direct three-vessel antegrade cerebral perfusion (MACP) or unilateral right axillary antegrade cerebral perfusion (uACP). Exclusion Criteria: * Incomplete key clinical, operative, or outcome data precluding analysis. * Preoperative modified Rankin Scale score of 4 or higher. * Ischemic stroke within 30 days before surgery. * Remote prior stroke history or unavailable prior-stroke status. * Patients managed with cerebral perfusion strategies other than MACP or uACP.
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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China Medical University Hospital
Taichung, 40447, Taiwan
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