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Heart surgery brain risk: low oxygen linked to memory trouble?

NCT ID NCT07361068

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study of 102 heart surgery patients examined whether drops in brain oxygen levels during surgery are linked to memory or thinking problems after the operation. Researchers used a special monitor to track brain oxygen and tested patients' thinking skills before and after surgery. The goal was to identify risk factors that could help prevent cognitive decline in future patients.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If it works, this could help identify patients at higher risk for cognitive decline after heart surgery, leading to better monitoring or preventive strategies.
What could go wrong
This is a small, completed observational study, not a treatment trial. The findings may not apply to all heart surgery patients or lead to direct changes in care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

102 people

The number who actually took part.

Started

Mar 2023

Finished

Mar 2024

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients undergoing open heart surgery with cardiopulmonary bypass under general anesthesia

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Planned elective CPB surgery * Provision of written informed consent * Absence of communication barriers that could interfere with preoperative and postoperative MMSE assessment * No history of cerebrovascular disease * Preoperative MMSE score ≥24 * Education level of at least high school * Absence of any frontal deformity that could hinder NIRS monitoring Exclusion Criteria: * Preoperative use of antipsychotic or antidepressant medications * Emergency cardiac surgery indication * Presence of ≥50% carotid artery stenosis

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Conditions

The condition(s) this trial relates to.

cognitive disorder Cognitive Dysfunction Postoperative Cognitive Complications

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Bursa Yuksek Ihtisas Traning and Research Hospital

    Bursa, 16000, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.