Heart surgery brain risk: low oxygen linked to memory trouble?
NCT ID NCT07361068
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study of 102 heart surgery patients examined whether drops in brain oxygen levels during surgery are linked to memory or thinking problems after the operation. Researchers used a special monitor to track brain oxygen and tested patients' thinking skills before and after surgery. The goal was to identify risk factors that could help prevent cognitive decline in future patients.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If it works, this could help identify patients at higher risk for cognitive decline after heart surgery, leading to better monitoring or preventive strategies.
- What could go wrong
- This is a small, completed observational study, not a treatment trial. The findings may not apply to all heart surgery patients or lead to direct changes in care.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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102 people
The number who actually took part.
- Started
-
Mar 2023
- Finished
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Mar 2024
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients undergoing open heart surgery with cardiopulmonary bypass under general anesthesia
- Ages
-
18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Planned elective CPB surgery * Provision of written informed consent * Absence of communication barriers that could interfere with preoperative and postoperative MMSE assessment * No history of cerebrovascular disease * Preoperative MMSE score ≥24 * Education level of at least high school * Absence of any frontal deformity that could hinder NIRS monitoring Exclusion Criteria: * Preoperative use of antipsychotic or antidepressant medications * Emergency cardiac surgery indication * Presence of ≥50% carotid artery stenosis
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Bursa Yuksek Ihtisas Traning and Research Hospital
Bursa, 16000, Turkey (Türkiye)
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