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Routine brain MRIs for stage IV breast cancer: helpful or not?

NCT ID NCT07357298

First seen Jan 29, 2026 · Last updated Jun 23, 2026 · Updated 29 times

Summary

This study looks at whether getting a brain MRI every 6 months can find cancer spread to the brain earlier in people with stage IV breast cancer who have no symptoms. About 156 participants will be randomly assigned to either scheduled scans or scans only when symptoms appear. The goal is to see if earlier detection changes treatment and improves quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Baptist Health South Florida

    NOT_YET_RECRUITING

    Miami, Florida, 33176, United States

    Contact

    Contact

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could show that regular brain scans help catch metastases earlier, potentially reducing the need for aggressive treatments like whole-brain radiation.

What could go wrong

This is an early-stage study with only 156 participants, so results may not apply to all patients. Routine scans could also cause unnecessary anxiety or lead to overtreatment without improving survival.

Conditions

The condition(s) this trial relates to.

breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.