Scientists use powerful MRI to map the healthy brain
NCT ID NCT00004577
First seen Jun 27, 2026 · Last updated Sep 01, 2026 · Updated 7 times
Summary
This study aims to improve MRI technology for imaging the brain. Researchers will test new scanning methods on 1,100 healthy adults aged 18 and older. Participants will have yearly MRI scans and may perform simple tasks like listening to sounds or tapping fingers. The goal is to create clearer images of brain structure and activity, which could eventually help diagnose and understand brain diseases.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to improved MRI methods that help doctors better understand and diagnose brain disorders.
- What could go wrong
- This is an early-stage observational study focused on technology development, not a treatment. Results may not directly benefit participants or lead to immediate clinical applications.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2000
- Lead sponsor
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A government research agency
The lead sponsor is the US National Institutes of Health.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Healthy Volunteer
- Ages
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18 to 120 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
* INCLUSION CRITERIA: * 18 years of age and older * in good general health * able to understand the procedures and requirements and give informed consent EXCLUSION CRITERIA: All Subjects will undergo a neurological physical and answer the Healthy volunteer form, and the most-recent version of the NMR safety screening form A subject will be excluded if he/she: 1. has any metal implant or objects of unknown identity or composition, or if it s known to be non-compatible with MRI, such as pacemakers, medication pumps, aneurysm clips, metallic prosthesis (such as heart valves or cochlear implants), certain orthopedic implants (pins and rods), shrapnel, or small metal fragments in the eye; 2. has claustrophobia; 3. cannot lie comfortably for up to 120 minutes; 4. underwent brain surgery or suffered a traumatic head trauma; 5. has migraines that require medication; 6. has ever been hospitalized for a psychiatric disorder; 7. has medical health problems such as pulmonary or airway disease, heart failure, coronary artery disease, and uncontrolled hypertension which would require physiological monitoring during the scan; 8. has a history of any medical condition that could result in an emergency medical situation while undergoing the MRI scan; 9. has hearing problems which would make it difficult to tolerate scanner noise; 10. is pregnant; 11. has body/make-up tattoos (e.g. lips, eyebrows, eyeliner). Each tattoo will be considered on a case-to-case basis, taking into account of the age and location of the tattoo; 12. has a sleep apnea diagnosis; 13. has a neurological disorder, such as Stroke, Parkinson s, and Epilepsy; 14. a member of the NINDS Laboratory of Functional and Molecular Imaging. The contraindications to MRI at the various field strengths are almost identical, except the 7 T also excludes subjects with gold dental crowns.
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Genom att skicka in godkänner du våra Användarvillkor
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
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