Brain electrodes link facial cues to mood in depression
NCT ID NCT06159595
First seen Nov 04, 2025 · Last updated Jun 19, 2026 · Updated 31 times
Summary
This completed Stanford study looked at whether video-recorded facial expressions and speech patterns can reflect a person's mood. Eleven adults with depression or epilepsy had electrodes temporarily placed in their brains to record brain activity. Researchers stimulated certain brain areas and measured changes in both facial behaviors and self-reported mood, aiming to find objective mood markers.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Stanford University
Stanford, California, 94305, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
intracranial electrodes
What this could lead to
If successful, this could lead to a new way to measure mood continuously and objectively using video, helping improve mental health treatments.
What could go wrong
This is a very small, early-stage study with only 11 participants. It is exploratory and may not produce clear or generalizable results.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.