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Heart Infection's hidden brain damage tracked over time

NCT ID NCT02252900

Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study followed 100 patients who had infectious endocarditis, a serious heart infection, to see how brain lesions found on MRI scans change over time. Researchers compared initial MRI results with follow-up scans and tested thinking and memory skills. The goal was to understand the long-term brain effects of this infection.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better predict and manage brain complications in endocarditis patients.
What could go wrong
This is an observational study with no treatment, so it won't directly improve patient outcomes. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2013

Finished

Jul 2017

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * History of Infective endocarditis treated in Bichat Claude Bernard hospital * Cerebral MRI performed during the acute phase of endocarditis * Resident in Metropolitan France * 18 years old or more Exclusion Criteria: * Refusal to participate * Contra indication to MRI scan * History of allergy to gadolinium * Pregnancy or lactating female * Lack of Social Security or CMU (recipient or beneficiary)

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Conditions

The condition(s) this trial relates to.

brain injury infective endocarditis subacute bacterial endocarditis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Infectious endocarditis

Contacts and locations

Locations

  • Groupe Hospitalier Bichat - Claude Bernard

    Paris, 75018, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.