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Brain insulin study in women may explain antipsychotic weight gain

NCT ID NCT06251635

First seen Apr 02, 2026 · Last updated May 22, 2026 · Updated 4 times

Summary

This study looks at how antipsychotic drugs change the way the brain responds to insulin in women, and whether this varies with menstrual cycle phase. Fifteen healthy women will receive the antipsychotic olanzapine or a placebo, plus insulin nasal spray, and undergo MRI scans. The goal is to understand why women on antipsychotics have higher rates of metabolic problems like diabetes.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre for Addiction and Mental Health (CAMH)

    RECRUITING

    Toronto, Ontario, M6J 1H3, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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