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New PET tracer aims to spot hidden brain proteins in movement disorders

NCT ID NCT06032026

First seen Nov 19, 2025 · Last updated May 24, 2026 · Updated 27 times

Summary

This early-phase study tests a radioactive tracer called 11C-HY-2-15 to see how it spreads through the body and whether it can detect abnormal alpha-synuclein protein in the brains of people with Multiple System Atrophy (MSA). Researchers will compare scans from people with MSA, Parkinson's disease, progressive supranuclear palsy (PSP), and healthy volunteers. The goal is to improve diagnosis of these brain disorders. About 70 adults aged 40-80 will take part across multiple U.S. sites.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19104, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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