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Meditation may reshape your brain in just 6 months

NCT ID NCT05455814

Knowledge-focused Sponsor: Beth Israel Deaconess Medical Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether a 21-minute daily meditation practice called Shambhavi Mahamudra Kriya can improve brain health. Researchers will measure brain activity, brain structure, and thinking skills in 77 adults aged 20-65 over 6 months. The goal is to see if this simple, seated meditation leads to a calmer, more focused brain.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Shambhavi Mahamudra Kriya meditation (a 21-minute seated breathing and meditation practice)
What this could lead to
If successful, this could show that a simple daily meditation practice measurably improves brain health and cognitive function.
What could go wrong
This is a small, early-stage study with only 77 participants, so results may not apply to everyone. It measures brain signals and structure, not clinical outcomes like disease prevention.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

77 people

The number who actually took part.

Started

Jan 2023

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Individuals between the ages of 20-65 years. * Subjects will be required to be able to understand study instructions and provide informed consent. * Currently residing in Massachusetts. Exclusion Criteria: * Non-English Speaking. (Justification: Meditation and cognitive assessment instruments are not validated in a sufficient range of languages, and the research team lacks polylingual capabilities or the financial resources to hire interpreters for the duration of all proposed assessments.) * Practicing meditation regularly for the past 6 months (3 or more times per week of practice regularly for the past 6 month). * History of psychiatric illness such as severe anxiety, severe depression, Schizophrenia or bipolar disorder. * History of any form of cognitive decline or neurological conditions such as dementia, Parkinson's disease, Alzheimer's disease, Huntington's disease, brain tumors, brain surgery. * Current use of cognition enhancing drugs * Current management for chronic pain. * History (within the last 5 years) of stroke/aneurysm. * Active history (within the last 5 years) of alcohol or drug abuse (\> 10 drinks per week). * Current pregnancy or planning to become pregnant in the next 6 months. * Currently enrolled in another interventional study that could impact the primary outcome, as determined by the PI. * Educational attainment below high school level or equivalent. * Significant visual impairment. Women of childbearing potential will be included as the intervention and the procedures in the study have minimal risks. There will be no enrollment exclusions based on sex, racial or ethnic factors. If a woman becomes pregnant during the course of the study and is willing to stay as a subject, MRI will not be conducted.

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Conditions

The condition(s) this trial relates to.

anencephaly

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Brain; agenesis Meditation

Contacts and locations

Locations

  • Beth Israel Deaconess Medical Centre

    Boston, Massachusetts, 02115, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.