Brain scans reveal dopamine disruption in coma patients
NCT ID NCT06930261
First seen May 14, 2026 · Last updated Jun 21, 2026 · Updated 4 times
Summary
This study uses advanced PET scans to examine how traumatic coma affects the brain's dopamine system. Researchers will compare three groups: people in a coma after severe head injury, those who have recovered from such an injury, and healthy volunteers. By imaging dopamine pathways, they hope to better understand why some people regain consciousness and others do not.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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CHU de Toulouse
RECRUITINGToulouse, France
Contact Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
LBT-999 (a radioactive tracer for PET imaging)
What this could lead to
If successful, this study could reveal how dopamine disruptions affect consciousness after traumatic coma, potentially guiding future treatments to aid recovery.
What could go wrong
This is an early-phase imaging study with only 55 participants. It is designed to observe brain changes, not to test a treatment, so direct patient benefits are unlikely.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.