Brain blood flow study aims to uncover clues about aging
NCT ID NCT06629077
First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 41 times
Summary
This study looks at how brain blood flow changes when healthy adults aged 55-69 breathe differently or shift posture, using MRI scans. Participants will also receive a single dose of prazosin or a placebo to see how it affects blood flow. The goal is to better understand the brain's response to reduced blood flow, which could inform future research on age-related conditions.
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This is a summary of
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Wisconsin
RECRUITINGMadison, Wisconsin, 53705, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Prazosin
What this could lead to
If successful, this could help scientists understand how brain blood flow changes with age and posture, potentially guiding future treatments for conditions like dizziness or fainting.
What could go wrong
This is a small, early-phase study with only 36 participants, so results may not apply to everyone. Prazosin can cause dizziness or low blood pressure.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.