Scientists peer into the brain to uncover secrets of movement disorders
NCT ID NCT04061135
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at brain activity in people with Parkinson's disease or essential tremor who are already scheduled for deep brain stimulation (DBS) surgery. Researchers want to understand how the brain handles both movement problems and non-motor issues like memory loss or depression. About 90 adults will take part, and the goal is to learn more—not to test a new treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 90 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2019
- Expected to finish
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Mar 2029
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Eligible for DBS surgery based on multi-disciplinary consensus review * Have a diagnosis of Parkinson's disease or Essential Tremor * A minimum of 18 years of age * Willingness to participate in the paradigms described in the protocol Exclusion Criteria: * Inability to provide full and informed consent * Are not surgical candidates due to co-morbid conditions or pregnancy * Have not undergone an adequate trial of conservative medical management * Have a clinical presentation for which DBS surgery is not indicated * Are not able to participate in study-related activities
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Alabama at Birmingham
RECRUITINGBirmingham, Alabama, 35233, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Reading the Brain's signals to predict who benefits from deep brain stimulation
- Hair-Thin electrodes tested to Fine-Tune brain stimulation
- Brain training through implanted electrodes aims to quiet Parkinson's tremors
- Can new brain stimulation patterns quiet stubborn tremors?
- AI hunts for early clues to Parkinson's and Alzheimer's progression
- Mapping the Brain's electrical signals to improve surgical precision