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Scientists scan coma Patients' brains to uncover secrets of consciousness

NCT ID NCT01620957

Knowledge-focused Sponsor: Institut National de la Santé Et de la Recherche Médicale, France Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at brain activity in 43 people in a coma after severe brain injury. Researchers used MRI scans to see how different brain regions communicate, aiming to understand what happens in the brain during coma and as people wake up. No treatment was given; the goal was simply to learn more about consciousness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

43 people

The number who actually took part.

Started

Jul 2012

Finished

Jul 2017

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

We will analyse DMN functional and anatomical connectivity in severely brain-injured patients in coma and during the first two month following brain injury. All patients will be admitted from one of the four Critical Care Units of University Teaching Hospital of Toulouse, France.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Brain-damaged patients in coma (trauma or anoxic origin). * Male and female, ranging in age from 18 to 75 years. Exclusion Criteria: * Withdrawal of consent from the patients (or the persons having legal responsibility for them). * Sedation or general anaesthesia during assessement period (\< 24 hours). * MRI contraindications

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Conditions

The condition(s) this trial relates to.

Coma ocular motor apraxia, Cogan type Persistent Vegetative State

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COMA

Contacts and locations

Locations

  • Institut National de la Santé et de la Recherche Medicale, U825

    Toulouse, Haute Garonne, 31059, France

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