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Box breathing may ease Procedure-Related discomfort

NCT ID NCT07328477

Symptom relief Sponsor: Acibadem University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a simple breathing technique called box breathing can help reduce anxiety, pain, and nausea in patients undergoing a procedure called ERCP. Seventy adults were randomly assigned to either learn the breathing technique or receive standard care. The technique involves breathing in, holding, breathing out, and holding again, each for four seconds. The goal is to see if this non-drug approach can improve patient comfort.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
box breathing technique
What this could lead to
If it works, this could offer a simple, drug-free way to help patients feel calmer and more comfortable during ERCP procedures.
What could go wrong
This is a small, single-center study with 70 participants. The results may not apply to all patients or settings, and the technique may not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

70 people

The number who actually took part.

Started

Jul 2025

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 18 years or older * Scheduled to undergo endoscopic retrograde cholangiopancreatography (ERCP) * Able to communicate verbally * Able to understand and perform the box breathing technique * Willing to participate and provide written informed consent Exclusion Criteria: * Cognitive impairment or psychiatric disorders affecting cooperation * Hearing or communication problems that prevent understanding instructions * Use of sedative or anxiolytic medication before ERCP other than standard sedation * Previous participation in breathing or relaxation training programs * Emergency ERCP procedures

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Conditions

The condition(s) this trial relates to.

agnosia anxiety anxiety disorder Nausea Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anxiety Endoscopic retrograde cholangiopancreatography Nausea Pain

Contacts and locations

Locations

  • Goztepe Prof. Dr. Suleyman Yalcin City Hospital

    Istanbul, 34730, Turkey (Türkiye)

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