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New colonoscopy prep powder could mean less laxative, same clean results

NCT ID NCT06514989

Symptom relief Sponsor: Changhai Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether a low-residue nutrition formula powder, taken with a smaller amount of laxative (2 liters), works as well as a standard low-residue diet with more laxative (3 liters) for cleaning the bowel before a colonoscopy. About 757 adults scheduled for colonoscopy took part. The goal was to see if the new approach causes fewer side effects like bloating or nausea while still providing a clear view for the doctor.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
low-residue full nutrition formula powder
What this could lead to
If it works, this could make bowel preparation for colonoscopy more tolerable by reducing the amount of laxative needed.
What could go wrong
This is a completed study, but it only compares two preparation methods; the new formula may not clean the bowel as well as the standard approach, and results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

757 people

The number who actually took part.

Started

Jul 2024

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * adult subjects between the ages of 18 and 75 who were scheduled for screening, monitoring, and diagnostic colonoscopy. Exclusion Criteria: * severe heart, brain, lung, kidney complications or a history of acute myocardial infarction within six months. * a history of abdominal or pelvic surgery, BMI \> 28 or BMI \< 18.5, inflammatory bowel disease, constipation (less than 3 bowel movements in the past week, with strenuous bowel movements, hard stool, small volume), or intestinal obstruction. * imaging and laboratory tests are highly suspicious of colorectal cancer or warning signs and symptoms of colorectal cancer: blood in the stool, black stool, unexplained anemia and significant weight loss, abdominal mass, and positive digital rectal examination.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bowel preparation for colonoscopy

Contacts and locations

Locations

  • Affiliated Hospital of Guizhou Medical University

    Guiyang, Guizhou, China

  • Affiliated Hospital of Jiangnan University

    Wuxi, Jiangsu, China

  • Ankang Central Hospital

    Ankang, Shanxi, China

  • Changhai Hospital, Naval Medical University

    Shanghai, Shanghai Municipality, 200433, China

  • East China Hospital, Fudan University

    Shanghai, China

  • Ganzhou People's Hospital

    Ganzhou, Jiangxi, China

  • Huizhou Central People's Hospital

    Huizhou, Guangdong, China

  • Jiangmen Central Hospital

    Jiangmen, Guangdong, China

  • Jiangsu Province Hospital

    Nanjing, Jiangsu, China

  • Jiangsu Provincial Hospital of Traditional Chinese Medicine

    Nanjin, Jiangsu, China

  • Jiangsu Subei People's Hospital

    Yangzhou, Jiangsu, China

  • Lu'an People's Hospital

    Lu'an, Anhui, China

  • Nanjing Gulou Hospital

    Nanjing, Jiangsu, China

  • Northern Theater General Hospital

    Shenyang, Liaoning, China

  • PLA 909 Hospital

    Quanzhou, Fujian, China

  • PLA 909 Hospital

    Zhangzhou, Fujian, China

  • Shandong Provincial Hospital

    Jinan, Shandong, China

  • Shanghai East Hospital

    Shanghai, Shanghai Municipality, China

  • Shanghai Seventh People's Hospital

    Shanghai, China

  • Shengli Oilfield Central Hospital

    Dongying, Shandong, China

  • The First Affiliated Hospital of Hebei North University

    Zhangjiakou, Hebei, China

  • The First Affiliated Hospital of Wenzhou Medical University

    Wenzhou, Zhejiang, China

  • The Second Affiliated Hospital of Nanchang University

    Nanchang, Jiangxi, China

  • The Second Affiliated Hospital of Wenzhou Medical University

    Wenzhou, Zhejiang, China

  • The Second Hospital of Hebei Medical University

    Shijiazhuang, Hebei, China

  • Yibin Second People's Hospital

    Yibin, Sichuan, China

  • the central hospital of Dalian

    Dalian, Liaoning, China

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