Which colonoscopy prep is easier on patients? new study aims to find out
NCT ID NCT07060222
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two oral bowel preparation agents—lactulose and sodium phosphate—to see which one leads to better colonoscopy quality, fewer side effects, and higher patient satisfaction. About 300 adults scheduled for a colonoscopy will take one of the two treatments before their procedure. The goal is to find a more comfortable and effective way to clean the colon.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
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About 300 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Sep 2025
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Indication for Scheduled Colonoscopy: Participants must have a valid clinical indication for undergoing a scheduled colonoscopy, such as part of a colorectal cancer screening program, evaluation of gastrointestinal symptoms, or follow-up of previously diagnosed colorectal conditions. * Ability to Provide Informed Consent: Participants must have the physical and mental capacity to understand the nature of the study and voluntarily provide informed consent to participate. Exclusion Criteria: * History of Intestinal Obstruction: Participants with a known or suspected history of intestinal obstruction will be excluded due to the potential risks associated with the administration of bowel preparation agents. * Known Intolerance to Lactulose or Sodium Phosphate: Participants with a known intolerance to lactulose or sodium phosphate will be excluded due to the risk of severe adverse reactions. * Pregnancy and Lactation: Pregnant or breastfeeding women will be excluded due to the lack of safety data on bowel preparation agents in this population. * Interfering Clinical Conditions (Comorbidities): Participants with medical conditions that could interfere with study participation or affect the interpretation of results will be excluded, such as decompensated heart failure, chronic renal or liver disease, and a history of colonic resection.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
4 sites in 2 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Antigüo Hospital Civil de Guadalajara "Fray Antonio Alcalde"
RECRUITINGGuadalajara, Jalisco, 44200, Mexico
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Hospital Gustavo Nelson Collado Ríos Panamá.
NOT_YET_RECRUITINGPanamá, Herrera Province, Panama
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Hospital Santo Tomas
NOT_YET_RECRUITINGBella Vista, Provincia de Panamá, 37, Panama
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Nuevo Hospital Civil de Guadalajara "Juan I. Menchaca"
NOT_YET_RECRUITINGGuadalajara, Jalisco, 44340, Mexico
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Other studies related to the condition(s) this trial covers.
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- Popular diabetes drugs may impact colonoscopy prep quality